antisynthetase syndrome

Antisynthetase Syndrome

Antisynthetase syndrome is a special type of dermatomyositis characterized by acute onset, interstitial pulmonary fibrosis, resistance to standard glucocorticosteroid therapy. The clinical picture consists of fever, signs of fibrosing alveolitis (cough, shortness of breath), Raynaud’s phenomenon (pallor and cyanosis of the fingers). Sometimes there is muscle weakness, arthralgia. The diagnosis is confirmed by the determination…

amyloidosis

Amyloidosis

Amyloidosis is a general, systemic disease of the body, in which a specific glycoprotein (amyloid) is deposited in organs and tissues with impaired function of the latter. With amyloidosis, the kidneys (nephrotic syndrome, edematous syndrome), heart (heart failure, arrhythmias), gastrointestinal tract, musculoskeletal system, skin can be affected. Possible development of polyserositis, hemorrhagic syndrome, mental disorders.…

allergic vasculitis

Allergic Vasculitis

Allergic vasculitis is an aseptic inflammation of the vascular wall caused by an allergic reaction to the effects of various infectious and toxic factors. The pronounced polymorphism of rashes and variants of the course  has led to the fact that many of its forms are isolated as separate diseases, among which there is a global…

alkaptonuria

Alkaptonuria

Alkaptonuria is a genetically determined metabolic disorder characterized by a congenital deficiency of the homogentizinase enzyme and leading to incomplete cleavage of homogentizic acid, its excretion with urine and deposition of this metabolite in tissues (skin, articular cartilage, tendons, sclera, etc.). Signs of alkaptonuria appear in childhood and include the release of urine rapidly darkening…

retroperitoneal tumors

Retroperitoneal Tumors

Retroperitoneal tumors are a group of malignant and benign neoplasms of mesodermal, neurogenic and embryogenic origin localized in the retroperitoneal space. Characterized by a long asymptomatic course. With large retroperitoneal tumors, dyspeptic disorders, urination disorders, shortness of breath, neurological symptoms and swelling of the lower extremities are observed. With malignant lesions in the late stages,…

Two popular drugs: never take them together

Two popular drugs: never take them together

Taking over-the-counter medications seems harmless to many, because their purchase does not require consultation and a prescription from a doctor. However, sometimes it is possible to combine medications incorrectly, which leads to negative consequences. Experts have named one “couple” that can cause damage to health. If you regularly take antihistamines to treat allergies, you should…

Omicron Mutations

Why Omicron Mutations are Dangerous

Too many mutations of the Omicron strain allow it to bind to human cells better than other coronavirus strains. This conclusion was reached by scientists from the University of British Columbia. Several mutations of the Omicron variant allow this strain of coronavirus to bind to human cells more effectively than previous versions of the virus.…