prion disease

Prion Disease

Prion disease are slowly progressive brain damage associated with infectious proteins (prions). Pathognomonic symptoms of these diseases are the development of dementia, behavioral, motor disorders, extrapyramidal disorders, cerebellar manifestations, myoclonia, other neurological and psychopathic signs. Diagnosis of nosologies includes clinical, laboratory, and instrumental criteria. Etiotropic treatment has not been developed at the present stage, pathogenetic and…

lumbosacral radiculitis

Lumbosacral Radiculitis

Lumbosacral radiculitis is a clinical symptom complex caused by degenerative-dystrophic changes and secondary inflammation of the spinal roots in the lumbar and sacral spine. It is manifested by variable pain syndromes: lumbalgia, lumbago and lumbago with sciatica. Diagnosis is based on complaints, the results of examination and palpation of the lumbar region, the presence of…

lumbosacral plexopathy

Lumbosacral Plexopathy

Lumbosacral plexopathy is a lesion of the nerve plexus of the same name. It may have an infectious, traumatic, toxic, autoimmune, iatrogenic etiology. Manifests plexalgia with the addition of muscle weakness and hypotension, tendon hyporeflexia and sensitivity disorders, and then trophic disorders in the lower limb on the affected side. Disease is diagnosed by a neurologist…

posttraumatic myelopathy

Posttraumatic Myelopathy

Posttraumatic myelopathy is a chronic neurodegenerative disease of the spinal cord that occurs after a spinal injury. The clinical picture of the disease depends on the level and nature of the damage, includes segmental and conductive motor and sensory disorders, musculotonic, reflex and pelvic disorders. Diagnostic search is carried out with the help of X-ray,…

post-concussion syndrome

Post-Concussion Syndrome

Post-concussion syndrome is a common complication of traumatic brain injury, observed mainly in concussion of the brain. It is manifested by fatigue, irritability, cephalgia, dizziness, slight intellectual decline, apathy, character change. Post-concussion syndrome is diagnosed according to clinical criteria after excluding other causes of such symptoms. Additional examinations (EEG, electrostagmography, MRI) are carried out for the…

postvaccinal encephalitis

Postvaccinal Encephalitis

Postvaccinal encephalitis is inflammatory changes in cerebral tissues that occur in connection with vaccination. Develops acutely on the 3-30 th day after vaccination. It begins with fever, vomiting, headache, convulsive attack, loss of consciousness; then focal symptoms occur: paresis, sensitive disorders, hyperkinesis, cerebellar syndrome. Diagnostic value has anamnesis data, assessment of neurological status, analysis of…

porencephalic cyst

Porencephalic Cyst

Porencephalic cyst is the formation of pathological cavities in the brain of different shapes and sizes filled with fluid. The disease occurs primarily in the prenatal period under the influence of genetic, teratogenic or hypoxic influences, as well as secondarily — against the background of encephalitis, cerebral hemorrhages. Porencephaly is manifested by epileptic seizures, decreased…

polyneuropathy in pregnancy

Polyneuropathy in Pregnancy

Polyneuropathy in pregnancy is a multiple lesion of mainly distal parts of peripheral nerve trunks that occurs in connection with pregnancy and completely regresses after its resolution. In the clinical picture, there are sluggish distal paresis, muscle hypotension, hyporeflexia, a decrease in complex types of sensitivity, with relative preservation of superficial ones. The diagnosis of “polyneuropathy…