Connective tissue dysplasia is a group of clinically polymorphic pathological conditions caused by hereditary or congenital defects in collagen synthesis and accompanied by impaired functioning of internal organs and the musculoskeletal system. Dysplasia is most often manifested by changes in body proportions, bone deformities, joint hypermobility, habitual dislocations, hyperelastic skin, valvular heart defects, vascular fragility,…
Buschke’s scleredema is a rare scleroderm–like disease characterized by indurative-fibrous changes in the skin. Clinically manifested by thickening, compaction of the skin of the face, neck, upper torso, leading to limited movement. The diagnosis is made on the basis of histological examination of the affected area of the skin. In some cases, treatment is not…
Systemic vasculitis unites a group of diseases in which there is inflammation and destruction of vascular walls, leading to ischemia of organs and tissues. Disease is represented by Takayasu arteritis, Wegener’s granulomatosis, nodular periarteritis, Behcet syndrome, obliterating thrombangiitis, giant cell arteritis, etc. Pathology is aggravated by damage to the skin, kidneys, heart, lungs, joints, organs…
Systemic scleroderma is a diffuse pathology of connective tissue, which is characterized by fibrotic-sclerotic changes in the skin, musculoskeletal system, internal organs and blood vessels. Typical signs of systemic scleroderma are Raynaud’s syndrome, skin thickening, masked face, telangiectasia, polymyositis, joint contractures, changes in the esophagus, heart, lungs, kidneys. Diagnosis of systemic scleroderma is based on…
Systemic lupus erythematosus is a chronic systemic disease with the most pronounced manifestations on the skin; the etiology of lupus erythematosus is not known, but its pathogenesis is associated with a violation of autoimmune processes, as a result of which antibodies to healthy cells of the body are produced. Middle-aged women are more susceptible to…
