Vesicular rickettsiosis is an acute transmissible natural focal infection. Characteristic signs are primary affect with central necrosis and abundant rash on the body. Fever, symptoms of general intoxication and a relatively benign course are noted. The main method of diagnosis is the isolation of the rickettsia gene material (PCR), the detection of antibodies to the…
Bubonic plague is a quarantine natural focal infection. The main clinical symptom is the presence of plague bubo. Nosology is characterized by high fever, severe intoxication, with immunosuppression, visceral lesion, generalization of infection is possible. Diagnostics is based on the detection of the pathogen in biological materials (microscopy, seeding, PCR), serological methods are uninformative, practically…
Typhoid fever is an acute intestinal infection characterized by a cyclical course with a predominant lesion of the intestinal lymphatic system, accompanied by general intoxication and exanthema. Typhoid fever has an alimentary pathway of infection. The incubation period lasts on average 2 weeks. The typhoid fever clinic is characterized by intoxication syndrome, fever, rashes of…
Brucellosis is a zoonotic infection characterized by multiple organ pathologies and a tendency to chronization. An important pathogenetic component of brucellosis is allergic reactivity. Brucella transmission occurs mainly by food and water, most often through milk and meat of infected animals. In cattle breeders, an aerial and contact pathway of brucellosis transmission can be realized.…
Brugiosis is a chronic biohelminthiasis from the group of filarioses with a transmissive transmission mechanism. The clinical picture in the acute phase of the disease is characterized by the presence of signs of desensitization of the body, the development of lymphangitis and lymphadenitis. Repeated relapses of the pathological process lead to the formation of elephantiasis…
Botulism is an acute food toxicoinfection that develops as a result of ingestion of botulinum toxin into the human body. Infection occurs in an alimentary way, most often when eating canned food containing botulism spores. Botulism is characterized by damage to the nervous system as a result of blocking of acetylcholine receptors of nerve fibers…
Chagas disease is a transmissible protozoal infection, the causative agent of which is pathogenic Trypanosoma cruzi, and the carrier is triatom bugs. The acute form is manifested by fever, headache and muscle pain, edema, rash, lymphadenitis, hepatosplenomegaly, cardiomegaly and myocarditis, meningoencephalitis; chronic – heart failure, megaesophagus, megacolon. The diagnosis is based on the data of…
Whipple’s disease is a rare infectious disease that occurs with a predominant lesion of the lymphatic system of the small intestine and the synovial membranes of the joints. The main clinical signs are diarrhea, fever, polyarthritis and joint pain, multiple enlargement of lymph nodes, lung, heart and central nervous system damage. Diagnosis is made by…
Lyme disease is a vector–borne infection, the causative agent of which is the Borrelia spirochete, which enters the body when an ixod mite bites. The clinical course includes local cutaneous (chronic migrating erythema) and systemic (fever, myalgia, lymphadenopathy, neuritis of peripheral and cranial nerves, meningitis, encephalitis, myelitis, myocarditis, pericarditis, oligoarthritis, etc.) manifestations. Confirmation of the…
Cat scratch disease is an acute zoonotic infection caused by the gram-negative bacterium Bartonella henselae, which enters the human body with bites or scratches of cats. A typical form occurs with primary affect in the form of papular-pustular rashes, regional lymphadenitis, fever, hepatosplenomegaly. There may be atypical forms of the disease – ocular, anginal, abdominal,…