Plummer’s disease is an endocrine pathology caused by the development of thyroid adenoma, which actively produces thyroid hormones. It is manifested by symptoms of hyperthyroidism: weight loss, shortness of breath, weakness, drowsiness, tachycardia, arrhythmia. The diagnostic complex includes consultation and examination of an endocrinologist, ultrasound and thyroid scintigraphy, blood test for thyroxine, triiodothyronine and thyroid-stimulating…
Cushing’s disease is a neuroendocrine disorder that develops as a result of damage to the hypothalamic-pituitary system, hypersecretion of ACTH and secondary hyperfunction of the adrenal cortex. The symptom complex characterizing Cushing’s disease includes obesity, hypertension, diabetes mellitus, osteoporosis, decreased function of the genital glands, dry skin, striae on the body, hirsutism, etc. For diagnostic…
Addison’s disease is a primary adrenal insufficiency (PAI), which is caused by the destruction of the glandular tissue of the adrenal glands and a decrease in hormone synthesis. The disease occurs against the background of autoimmune pathologies, damage to the endocrine glands by the tuberculous process. Classic symptoms include hyperpigmentation of the skin, general and…
Silent thyroiditis is a thyroid disease characterized by lymphoid infiltration and an immunodestructive process in glandular tissues. It is manifested by symptoms of transient thyrotoxicosis in the absence of pain syndrome. Patients complain of irritability, fatigue, general weakness, weight loss, palpitations. Diagnostics includes ultrasound and thyroid scintigraphy, blood tests for T4, TSH, anti-TPO. Medical treatment…
Autoimmune thyroiditis (AIT) is a chronic inflammation of thyroid tissue that has an autoimmune genesis and is associated with damage and destruction of follicles and follicular cells of the gland. In typical cases, autoimmune thyroiditis has an asymptomatic course, only occasionally accompanied by an increase in the thyroid gland. Diagnosis of autoimmune thyroiditis is carried…
Autoimmune polyglandular syndrome (APGS) is an autoimmune endocrinopathy that occurs with simultaneous primary multiple lesions of the endocrine glands and other organs. With APGS type 1, there is adrenal insufficiency, candidiasis of the skin and mucous membranes, hypoparathyroidism; APGS type 2 proceeds with the development of adrenal insufficiency, hyper- or hypothyroidism, insulin-dependent diabetes mellitus, primary hypogonadism,…
Thyroid dysgenesis are congenital pathologies, including violations of the position, quantity, structure of the organ, as well as residual embryonic formations. Depending on the type of thyroid defect, it may be accompanied by euthyroidism, signs of hypo- or hyperthyroidism, choking, coughing, shortness of breath. The diagnosis of anomalies is carried out using ultrasound, fine needle…
Amiodarone-induced thyropathies (AmIT, AIT) are a group of thyroid pathologies caused by prolonged use of the antiarrhythmic drug amiodarone. The course is often asymptomatic, sometimes mild and moderate signs of hyperthyroidism (irritability, feeling of heat, tachycardia, tremor) or hypothyroidism (chilliness, weakness, drowsiness, fatigue) develop. Diagnostics includes blood tests for thyroxine, triiodothyronine and thyroid-stimulating hormone, scintigraphy…
Primary aldosteronism (aldosteroma, Conn’s syndrome) is a hormonally active tumor of the glomerular epithelium of the adrenal cortex, leading to the development of clinical Conn syndrome – primary aldosteronism. Among the symptoms are cardiovascular (arterial hypertension, headaches, cardialgia, visual impairment), neuromuscular (myopathy, myalgia, paresthesia, convulsions), renal (polyuria, polydipsia, isostenuria). The diagnosis is established by the characteristic…
Acromegaly is a pathological enlargement of individual parts of the body associated with increased production of somatotropic hormone (growth hormone) by the anterior pituitary lobe as a result of its tumor lesion. It occurs in adults and is manifested by enlargement of facial features (nose, ears, lips, lower jaw), enlargement of feet and hands, constant…