Dermatomyositis is a diffuse inflammatory pathology of connective tissue with a progressive course, characterized by damage to smooth and striated muscle fibers with impaired motor functions, skin involvement, small vessels and internal organs. In the absence of a skin syndrome, the presence of polymyositis is indicated. The clinic of dermatomyositis is characterized by polyarthralgia, severe…
Granulomatosis with polyangiitis (Wegener’s granulomatosis) is a systemic necrotic vasculitis of small veins and arteries with the formation of granulomas in the vascular walls and surrounding tissues of the respiratory tract, kidneys, etc. organs. Disease is characterized by ulcerative-necrotic rhinitis, changes in the larynx, paranasal sinuses, infiltration of lung tissue with decay, rapidly progressing glomerulonephritis,…
Gonococcal arthritis is a specific inflammatory lesion of the joints that develops with a disseminated form of gonorrhea. Disease is accompanied by chills and fever; edema, hyperemia and rashes in the affected joints, limited movement, arthralgia. The diagnosis is based on the data of anamnesis, joint radiography, serological and microbiological studies. In the acute period…
Homocystinuria is a hereditary defect of metabolism, the primary link of which is a violation of the metabolism of sulfur-containing amino acids, leading to damage to the nervous, musculoskeletal and cardiovascular systems. Homocystinuria is accompanied by mental retardation, convulsive syndrome, lens subluxation, cataract, glaucoma, optic nerve atrophy, chest deformity, scoliosis, arachnodactyly, arterial and venous thrombosis.…
Hypertrophic pulmonary osteoarthropathy is a secondary lesion of the osteoarticular apparatus that develops against the background of chronic inflammatory or neoplastic processes. Hypertrophic pulmonary osteoarthropathy is characterized by deformation of the nail phalanges by the type of “drumsticks”, bone pain, arthralgia, swelling and stiffness of the joints, vegetative disorders (sweating of the palms and feet,…
Hydroxyapatite deposition disease is an inflammatory lesion of one or more joints associated with the deposition of calcium hydroxyapatite in its periarticular tissues. It is clinically manifested by restriction of movements in the joint, local soreness and swelling of tissues at the places of attachment of tendons to the joint. The most common lesion of the…
Hemochromatosis is a hereditary polysystemic disease accompanied by active absorption of iron in the gastrointestinal tract and its subsequent accumulation in internal organs (heart, pancreas, liver, joints, pituitary gland). The hemochromatosis clinic is characterized by bronze pigmentation of the skin and mucous membranes, the development of liver cirrhosis, diabetes mellitus, cardiomyopathy, arthralgia, sexual dysfunction, etc.…
Hemosiderosis is a disease of the pigmented dystrophy group characterized by excessive accumulation of the iron–containing pigment hemosiderin in the tissues of the body. There are local forms of the disease (cutaneous and pulmonary form) and general (with the deposition of hemosiderin in the cells of the liver, spleen, kidneys, bone marrow, salivary and sweat…
Allergic purpura is a systemic aseptic inflammation of the vessels of the microcirculatory bed with a predominant lesion of the skin, joints, gastrointestinal tract and renal glomeruli. It proceeds with the phenomena of hemorrhagic or urticaria rash, arthralgia, abdominal pain syndrome, hematuria and renal insufficiency. Diagnosis is based on clinical symptoms, laboratory data (blood, urine,…
Viral arthritis is a joint lesion in various viral infections. Clinical manifestations include arthralgic syndrome, local swelling and movement difficulties. Joint stiffness resembling rheumatoid arthritis is possible. The diagnosis is based on the symptoms and laboratory signs of a particular viral infection. Treatment in most patients is limited to symptomatic therapy with the use of…