Nervous diseases are diseases that develop as a result of damage to the brain and spinal cord, as well as peripheral nerve trunks and ganglia. Nervous diseases are the subject of study of a specialized field of medical knowledge – neurology. Since the nervous system is a complex apparatus that connects and regulates all organs and systems of the body, neurology closely interacts with other clinical disciplines such as cardiology, gastroenterology, gynecology, ophthalmology, endocrinology, orthopedics, traumatology, speech therapy, etc. The main specialist in the field of nervous diseases is a neurologist.
ND can be genetically determined (Rossolimo-Steinert-Kurschmann myotonia, Friedreich’s ataxia, Wilson’s disease, Pierre-Marie ataxia) or acquired. Congenital malformations of the nervous system (microcephaly, basilar impression, Kimberly anomaly, Chiari anomaly, platybasia, congenital hydrocephalus), in addition to hereditary factors, can lead to unfavorable conditions of intrauterine development of the fetus: hypoxia, radiation, infection (measles, rubella, syphilis, chlamydia, cytomegaly, HIV), toxic effects, the threat of spontaneous termination of pregnancy, eclampsia, Rh conflict, etc. Infectious or traumatic factors affecting the nervous system immediately after the birth of a child (purulent meningitis, asphyxia of a newborn, birth trauma, hemolytic disease) often lead to the development of such nervous diseases as cerebral palsy, childhood epilepsy, oligophrenia.

Acquired ND are often associated with infectious lesions of various parts of the nervous system. As a result of infection, meningitis, encephalitis, myelitis, brain abscess, arachnoiditis, multiple encephalomyelitis, ganglioneuritis and other diseases develop. A separate group consists of traumatic etiology: TBI, spinal cord injury, traumatic neuritis. ND that occur in old age are mainly caused by vascular changes (dyscirculatory encephalopathy, TIA, ischemic stroke, hemorrhagic stroke), less often by metabolic disorders (Parkinson’s disease). The incidence of oncological nervous diseases remains high. The limited space inside the skull or spinal canal leads to the fact that even benign tumors of this localization (astrocytoma, craniopharyngioma, ganglioneuroma) have a malignant course. In addition, the problematic nature of complete removal of CNS tumors causes their frequent recurrence.

Clinical manifestations directly depend on which part of the nervous system was involved in the pathological process. Thus, nervous diseases with brain damage can be accompanied by headache, dizziness, gait and coordination disorders, speech disorders, hearing and vision loss, paresis and paralysis of a central nature, changes in the psyche. Nervous diseases associated with spinal cord pathology are manifested by motor and sensory disorders below the lesion level. Diseases of the peripheral nervous system (trigeminal neuralgia, facial neuritis, intercostal neuralgia, cervical plexitis, polyneuropathies, radial nerve neuropathy, femoral nerve neuropathy, etc.) are characterized by pain syndrome, sensitivity disorders, muscular atrophy, motor disorders, vegetative and trophic changes in the innervation zone of the affected nerve.

The foundation of instrumental diagnostics traditionally consists of such studies as radiography of the spine, Echo-EG, EEG, REG, electromyography, in children of the 1st year of life – neurosonography. They are replaced by more accurate diagnostic methods: computed tomography, MRI, PET of the brain, ultrasound of the vessels of the head, duplex scanning. And, if REG and echoencephalography, as methods of diagnosing nervous diseases, gradually lose their significance, then EMG and EEG remain indispensable. They make it possible to identify functional changes occurring in many that are not diagnosed by neuroimaging methods. In some nervous diseases, diagnostic search requires lumbar puncture, stereotactic biopsy, puncture of the ventricles of the brain, and other diagnostic operations. Since the nervous system is closely interconnected with other organs and systems of the body, for a more accurate diagnosis of nervous diseases, a neurologist (a pediatric neurologist) often needs consultations from other specialists: an ophthalmologist, an endocrinologist, a cardiologist, an orthopedist, etc.

Treatment as a rule, includes a whole range of measures aimed not only at combating the cause of the disease and its etiopathogenetic mechanisms, but also at maximum recovery of the neurological deficit resulting from the disease. For this purpose, physiotherapy, physical therapy, mechanotherapy, reflexology, manual therapy are widely used in the treatment of nervous diseases. Treatment of aneurysms, tumors, intracerebral hematomas, abscesses and cysts of the brain requires surgical intervention. In some cases, surgical treatment is used for epilepsy and Parkinson’s disease. Brain surgeries and spinal cord interventions are performed by neurosurgeons. They carry out modern surgical treatment of nervous diseases with the help of minimally invasive microsurgical techniques and under the control of neuroimaging. Methods of functional neurosurgery have been developed that are successfully used for torsion dystonia, cerebral palsy, Huntington’s chorea and other nervous diseases accompanied by muscle tone disorders, tremor or hyperkinesis.
You can learn more about the causes, symptoms, methods of diagnosis and treatment of individual nervous diseases in the corresponding section of the Medical Directory of Diseases. The Medic Journal website also provides descriptions of the main hardware studies that help diagnose various nervous diseases.

Ganglioneuroblastoma

Ganglioneuroblastoma is a malignant neurogenic tumor containing neuroblasts and ganglion cells at various stages of differentiation. Disease is characterized by anorexia, weight loss, fever, symptoms of excess catecholamines (increased blood pressure, sweating, facial hyperemia, tachycardia). Depending on the localization of the tumor, symptoms of compression of the abdominal cavity or mediastinum, focal neurological symptoms may…

Ganglioneuroma

Ganglioneuroma (ganglioma, ganglionic neuroma, gangliocytoma) is a benign tumor formed from elements of sympathetic nerve nodes (ganglia). Disease can have a very different localization. Most often it is associated with various parts of the spine, can be located in the brain, less often — in the adrenal glands, gastrointestinal tract, skin, bladder wall. The clinical…

Ganglioneuritis

Ganglioneuritis is an inflammatory lesion of a nerve node (ganglion) with the involvement of nerve trunks associated with it in the inflammatory process. The clinical picture consists of a pronounced pain syndrome, sensitivity disorders, vasomotor, neurotrophic and vegeto-visceral disorders. It has its own characteristics depending on the localization. Disease is diagnosed mainly on the basis…

Hypothalamic Hamartoma

Hypothalamic hamartoma is a rare benign hypothalamic tumor that resembles a gangliocytoma in histological characteristics. Etiological factors are not precisely established. The neoplasm is manifested by epileptic seizures, a decrease in cognitive abilities, and an advance in the pace of puberty. To diagnose hypothalamic neoplasia, electroencephalography and cerebral MR scanning are required. Treatment includes anticonvulsants,…

Secondary Parkinsonism

Secondary parkinsonism is a clinical term that combines all cases of the appearance of parkinsonism syndrome caused by the influence of various factors affecting the central nervous system or the presence of a primary disease. Unlike Parkinson’s disease, secondary Parkinsonism has a more acute onset, is characterized by the initial symmetry of Parkinsonian manifestations and…

Paramyotonia Сongenita

Paramyotonia congenita is a separate clinical variant of myotonia inherited in an autosomal dominant way and characterized by the occurrence of myotonic episodes under the influence of cold. In the clinic of the disease, there are also paroxysms of transient muscle weakness. The diagnostic algorithm includes assessment of neurological status, biochemical blood examination, electroneuromyography, genealogical…

Congenital Myopathy

Congenital myopathy is a congenital disease caused by genetically determined disorders in the structure of muscle tissue. Disease is manifested by diffuse muscle weakness and a decrease in muscle tone, the severity of which varies significantly depending on the type of myopathy. In severe cases, congenital myopathy can lead to the death of a child…

Inflammatory Polyneuropathy

Inflammatory polyneuropathy is a multiple lesion of nerve trunks, the substrate of which is an inflammatory reaction of autoimmune genesis. It is manifested by rapidly or slowly progressive sluggish paresis with sensitivity disorder, sometimes with damage to the cranial nerves, paralysis of the respiratory muscles. Diagnostics is carried out using electrophysiological studies, analysis of cerebrospinal…

Inflammatory Myopathy

Inflammatory myopathy is an inflammatory process that occurs mainly in skeletal muscles and leads to their degenerative changes. Disease is characterized by muscle weakness, muscle pain, a sharp decrease in the volume of active movements, the development of contractures, compaction and swelling of muscles. Of the diagnostic methods, the most informative is the determination of…

Intracranial Hypertension

Intracranial hypertension is a syndrome of increased intracranial pressure. It can be idiopathic or develop with various brain lesions. The clinical picture consists of headache with pressure on the eyes, nausea and vomiting, sometimes — transient visual disturbances; in severe cases, there is a violation of consciousness. The diagnosis is made taking into account clinical…