hemoblastosis

Hemoblastosis

Hemoblastosis are bone marrow and extra-bone marrow neoplastic processes represented by two groups of diseases – myeloproliferative (leukemia) and lymphoproliferative (hematosarcoma). Hyperplastic, intoxication, hemorrhagic, anemic, immunodeficiency syndromes are common for all forms. Diagnosis includes a general blood test; sternal puncture, trepanobiopsy, lymph node biopsy with examination of the material; instrumental studies (ultrasound, radiography). Treatment of…

hairy cell leukemia

Hairy Cell Leukemia

Hairy cell leukemia is a chronic B-cell lymphoproliferative process that occurs with a predominant lesion of the bone marrow and spleen. Clinically manifested by hepatosplenomegaly, lymphadenopathy, lymphocytosis with “hairy” lymphocytes, pancytopenia. The diagnosis is established taking into account the data of the blood picture, immunophenotyping of lymphocytes, ultrasound / CT of abdominal organs, bone marrow…

thrombotic microangiopathy

Thrombotic Microangiopathy

Thrombotic microangiopathy is a polysyndromic pathology that combines thrombocytopenia, hemolytic anemia, arteriole occlusion with the development of ischemic organ lesions. Clinically, it proceeds with fever, bleeding, neurological disorders, abdominal syndrome. Possible development of TIA, myocardial and kidney infarction, hepatitis, mesenteric ischemia. Diagnosis is based on the study of blood (UAC, platelets, LDH, metalloproteinase activity), kidney…

willebrand disease

Willebrand Disease

Willebrand disease is a congenital pathology of hemostasis, manifested by quantitative and qualitative deficiency of Willebrand plasma factor and increased bleeding. Willebrand disease is characterized by spontaneous formation of subcutaneous petechiae, ecchymoses; recurrent bleeding from the nose, gastrointestinal tract, uterine cavity; excessive blood loss after injuries and operations, hemarthrosis. The diagnosis is established according to…