Systemic lupus erythematosus is a chronic systemic disease with the most pronounced manifestations on the skin; the etiology of lupus erythematosus is not known, but its pathogenesis is associated with a violation of autoimmune processes, as a result of which antibodies to healthy cells of the body are produced. Middle-aged women are more susceptible to…
Synovitis is an inflammatory process in the synovial membrane, accompanied by an accumulation of fluid (effusion) in the joint cavity. Pathology can develop as a result of trauma, infection, allergies, certain blood diseases, endocrine diseases and metabolic disorders. It is manifested by pain, an increase in the volume of the joint, weakness and malaise. When…
Synovial sarcoma is a malignant tumor associated with atypical transformation and proliferation of cells of the synovial membrane of joints, mucous bags and tendon sheaths. The most typical lesion of the lower extremities. Tumor metastasis occurs mainly by lymphogenic pathway. To diagnose, X-ray and angiographic examination of the lesion area, computed tomography, radioisotope scanning, biopsy,…
Sharpe’s syndrome is a systemic polysyndromic disease that combines individual manifestations of systemic lupus erythematosus, dermatomyositis, and scleroderma. Pathology occurs with joint, muscle, skin, visceral symptoms, Raynaud’s and Sjogren’s syndromes. The diagnosis can be established if autoantibodies to ribonucleoprotein, an immunological marker of the disease, are present in the blood of patients. The treatment lends…
Churg-Strauss syndrome is an inflammatory and allergic lesion of small and medium vessels (capillaries, venules, arterioles), occurring with the formation of necrotizing eosinophilic granulomas. Syndrome is characterized by hypereosinophilia, damage to the bronchopulmonary system, heart, gastrointestinal tract, central and peripheral nervous system, skin and joints. The diagnosis is based on the data of anamnesis, clinical…
Felty syndrome is a symptom complex that includes the main triad of signs: rheumatoid arthritis, splenomegaly and leukopenia. In addition to these symptoms, the course of Felty syndrome is accompanied by fever, muscular atrophy, pigmentation and ulcers on the skin of the shins, polyserositis, polyneuropathy, episcleritis, lymphadenopathy, hepatomegaly, a tendency to infectious diseases. In the…
Raynaud’s syndrome is a vasospastic disease characterized by paroxysmal disorder of arterial circulation in the vessels of the extremities (feet and hands) under the influence of cold or emotional excitement. Disease develops against the background of collagenoses, rheumatoid arthritis, vasculitis, endocrine, neurological pathology, blood diseases, occupational diseases. Clinically, pathology is manifested by seizures, including successive…
Goodpasture syndrome is an autoimmune pathology characterized by the formation of autoantibodies to the basal membranes of the renal glomeruli and pulmonary alveoli. Clinically, disease is manifested by recurrent pulmonary bleeding, progressive glomerulonephritis and renal insufficiency. The diagnosis is confirmed by the detection of antibodies to the glomerular basement membrane (Anti GBM), kidney and lung…
SAPHO syndrome is a chronic disease of unclear etiology, combining bone and joint (arthritis, synovitis, hyperostosis, osteitis) and skin changes (pustulosis, acne, psoriasis, hydradenitis). Clinically manifested by psoriatic and pustular rashes on the skin of the palms and feet, conglobate acne, pain in the chest, joints, spine, sacroiliac joint. Diagnosis is based on detectable laboratory…
Reiter’s syndrome is a rheumatic disease characterized by a combined lesion of the urogenital tract (urethritis and prostatitis), joints (mono– or polyarthritis) and the eye mucosa (conjunctivitis), developing sequentially or simultaneously. Reiter’s syndrome is based on an autoimmune process caused by an intestinal or genitourinary infection. Diagnostic criteria are the connection with the transferred infection,…
